BDG LifeSciences is a distinguished bioinformatics company established in 2010 and operates globally. Headquartered in India the company specializes in facilitating workshops, training programs, novel & innovative research projects, and online courses in technologies of bioinformatics & life science. The company is registered under the Ministry of MSME (Micro, Small, and Medium Enterprises), Government of India, with the registration number UDYAM-UP-01-0019151. Recently, BDG Lifesciences, India has authorized BBR Group Pty Ltd., Australia (ACN 608 550 849), to operate its programs in Australia & New Zealand.
With a focus on practical application of technology, where participants work on their own computer/laptop on software/servers,  BDG LifeSciences has been a leader in the sector for the last 14 years.
Since its inception, BDG LifeSciences has successfully educated a diverse range of participants globally, including students, scientists, faculty members, professors, and corporate executives.

Innovation & creativity is an integral part of BDG Lifesciences and we always launch new programs on the newest topics. Now advancing in the technology we have launched a 5-day Technical Training in Chimeric Antigen Receptor (CAR) T-Cells for Cancer Immunotherapy.

INTRODUCTION

Chimeric Antigen Receptor (CAR) T-cell therapy is a type of immunotherapy that uses a patient’s own genetically modified T-cells to find and kill cancer cells. Over the recent years CAR T-cell Therapy has generated substantial excitement among oncologists. They have shown the ability to eradicate tumors in people with advanced leukemias and lymphomas and to keep the cancer at bay for many years. Six CAR T-cell therapies have been approved by FDA since 2017. Computational design of CAR is essential for better treatment outcomes.

This program will be an extensive hands-on training program in which everyday 120-150 minutes of live session will be conducted by Dr Shahul Hameed and participants will run the processes (insilico) on their own computer systems with complete learning of this revolutionary technology. 

Video recording of each session will be provided at the end of the session to give the user a unique learning experience. On successful completion of the course participation certificate will be awarded.

TOPICS

• Tumor specific &Tumor Associated T-cell antigens and epitopes. 
• Identifying tumor antigens by screening a tumorcDNA expression library against cancer sera.
• Selection of scFvAntibody. Fragments for CAR-T Cell Therapy from Phage Display Libraries.
• Structure-guided engineering of the affinity and specificity of CARs against Tumor antigens.
• Computationally Guided Design of Single-Chain Variable Fragment.
• Chimeric Antigen Receptor Design & Construction.
• Intracellular signaling pathways of the CARs.
• Machine Learning in CAR sequence Optimization and Design.
• Generating synthetic CAR using deep learning.
• CRISPR CAS in CAR T-cell therapy: knock-in and immune-checkpoint.
• Universal CAR T-cells

OUTCOME OF THIS PROGRAM: Participants will learn

• Basic principles of chimeric antigen receptor design for CAR T-cell therapy.
• The participant will be able to design Chimeric Antigen Receptor for a given tumor.
• Optimize CAR for better expression on T-cells and Tumor cell killing activity.
• Reduce Toxicity of CAR T-cell therapy.

TARGET AUDIENCE

Student: Bachelor, Masters, PhD, MBBS, MD students as well as Faculty and Professors from Microbiology, Biochemistry, Biotechnology, Immunology, Medicine, Pharmacy, Pharmaceutical Chemistry, Biomedical Technology, Genetics, Bioinformatics, Plant Science and Life Sciences.

Professionals: Resident Doctors, Biotechnology, Bioinformatics, Medicine and Pharmaceutical scientists from industry, academia, and regulatory agencies. Hands-on exercises will be performed individually using software tools on your own laptops. (no prior experience required).

RESOURCE PERSON

Dr. Shahul Hameed is a researcher and his research involves developing CRISPR based gene therapy for Muscular dystrophy and Sickle Cell Anaemia. He is also involved in the development of novel delivery systems for gene therapy. His research interest extends to design of mRNA based therapeutics and design of Artificial Intelligence based Digital health & Imaging tools. In Collaboration with Dystrophy Annihilation Research Trust, his lab was involved in gene editing of DMD gene for development of CRISPR based therapeutics. [Nov 2018 to Aug 2022]

He has worked as Senior Assistant Professor at B.S. Abdur Rahman Crescent University, Chennai and earlier at Bannari Amman Institute of Technology, Erode. He was involved in teaching biotechnology subjects like Protein Engineering, Genomics and Proteomics, Structural Biology, Pharmaceutical Biotechnology, Genetic Engineering and Chemical Reaction Engineering to students. His research work involved Drug Design against S100A4 oncoprotein. Further development of Machine Learning based tools for predicting thermodynamic stability of enzyme mutants. He was selected through ERASMUS to conduct workshops on drug design and protein engineering at University of Nottingham, UK.

He is a PhD in Biological Sciences from Indian Institute of Science(IISc), Bangalore. At IISc, his research work involved Protein Engineering and Structural Characterization of the engineered mutants using Nuclear magnetic resonance spectroscopy and other biophysical methods. His research work also involved characterization of Protein-Protein interactions using experimental techniques, like NMR and Mass spectrometry, genetic engineering and Computer simulations.

He did his postdoctoral training at Tata Institute of Fundamental Research, Mumbai. There his work involved development of novel NMR techniques to study huge protein complexes. His work also involved Cloning, Protein Expression and Purification of motor proteins.

REGISTRATION STEPS:

1. Click on register tab.
2. This will take you to this link- https://events.humanitix.com/bdg-lifesciences-training-programs/tickets
3. You will see the Training Programs and their fee, scroll down to see the list of all available training programs.
4. For the training which you want to register, click 1 for 1 participant, 2 for 2 participants and so on and then click Continue.
5. Fill in the required attendee information and proceed to payment.
6. Complete the payment process, and you will receive your registration/ticket via email.

T & C

• After registering, please email to info@bdglifesciences.com with your preferred start date and choose one of the following time slots: 6:30 AM–8:00 AM India time or 9:30 PM–11:00 PM India time.
• Kindly note that the time of the sessions will be 60-90 minutes everyday. 
• Once you register, please allow us 2-5 working days to make your training schedule,i.e. dates and time.
• Please provide a GMAIL ID for registration as the recorded video session will be provided on YouTube. Kindly provide that email ID by which you use YouTube.
• Since the training is a one-on-one live session with a trainer on Zoom, you'll need to attend, allowing for practical hands-on learning, real-time explanations, and direct query resolution for a better learning experience.
• At the end of each session, you will receive a video recording, allowing you to review the steps as many times as needed to enhance your learning and master the topics and tasks.
• BDG Lifesceiences (OPC) Private Limited is registered under Ministry of MSME(Micro, Small and Medium Enterprises), Government of India with Registration Number:UDYAM-UP-01-0019151 hence the certificate will be provided of it. BBR Group Pty Ltd, Australia (ACN-Australian Company Number-608 550 849) has the franchisee of BDG Lifesciences to run its programs in Australia & New Zealand.
• The certificate will be issued as per the details which you will provide in the registration form while registering before payment.
• We want to make sure that you learn properly hence the training certificate will be given ONLY on successful completion of all the tasks given by the trainer.
• The certificates of all our Online programs are sent by email(softcopy) which has a unique barcode. You can take a print of that on heavy cardstock or photo paper and get it laminated if required.
• The registration is NON-REFUNDABLE and NON-TRANSFERABLE.
• BDG Lifesciences (OPC) Pvt. Ltd., India and BBR Group Pty Ltd Australia reserves the right of admission in all our programs.
• If you are removed or your registration is canceled then there will be no answer to that. We have our own reasons for such an act of ours. If we do not wish to give this workshop to any participant then we will refund their amount.
• To view the pictures of our previous events click here-1 and click here-2. To view, the listing of upcoming events kindly click here and our previous workshops can be viewed here. To view the video feedback of our previous events kindly visit our YouTube Channel
• You should also read the Terms & Conditions page as well as the FAQs page. For any assistance kindly chat with our AI Assistant BioBot on the website www.bdglifesciences.com